Ornopain 4mg Tablet

✔️ Uses of Ornopain 4

• Pain Relief
• Arthritis

✔️ Side Effects of Ornopain 4

• Fever
• Skin Rash
• Increased Blood Pressure
• Increased Heart Rate
• Nausea Or Vomiting
• Gastrointestinal Bleeding
• Headache
• Dizziness

✔️ Word of Advice: Ornopain 4

• Ornopain 4 is used for the treatment and prevention of conditions such as swelling, stiffness and joint pain, postoperative pain, acute gout, and acute musculoskeletal conditions.
• The effect of Ornopain 4 can be observed within 30 to 60 minutes of administration.
• Take Lornoxicam as instructed by the doctor. Ornopain 4 should be taken before/after food with an adequate amount of water. Do not consume more or less than the quantity prescribed by the doctor.
• The effect of this medicine lasts for an average duration of 24 hours.
• Ornopain 4  may cause dizziness. Drive only if you feel alert and safe.
• Not recommended for children under 18 years, as safety and effectiveness have not been established.
• You experience stomach pain or any signs of gastrointestinal bleeding, such as blood in stools.

✔️ How does Ornopain 4 work?

By blocking the COX enzymes, Lornoxicam decreases the formation of prostaglandins, leading to a reduction in pain, inflammation, and fever, which is why it is effective in treating conditions like arthritis, osteoarthritis, spondylitis, and other painful inflammatory disorders.

✔️ Pharmacology

COX Enzyme Inhibition:

• COX-1 is primarily involved in the production of prostaglandins that protect the stomach lining and support kidney function.
• COX-2 is induced during inflammation and is responsible for the production of prostaglandins that mediate pain, swelling, and fever.
• Decreased Prostaglandin Synthesis:
  By inhibiting both COX-1 and COX-2, Lornoxicam reduces the synthesis of prostaglandins—chemical messengers that are involved in inflammation, pain, and fever.
  • Pain Relief: Prostaglandins play a significant role in pain signaling. With fewer prostaglandins being produced, there is a reduction in pain sensation.
  • Anti-inflammatory Effect: Prostaglandins also promote inflammation, so their reduction helps to decrease swelling and redness in inflamed tissues.

✔️ Dosage & Administration of Ornopain 4

1. Pain Relief:
   • 8–16 mg per day, divided into doses.
2. Osteoarthritis/Rheumatoid Arthritis:
   • 12 mg daily, split into 2–3 doses with equal intervals.

• Administration:
  • Taken orally with or after food to minimize stomach irritation.

✔️ Interaction

Interaction with Alcohol (Ethanol):

• Minimize or avoid alcohol while taking Lornoxicam, as alcohol can increase the risk of stomach irritation, bleeding, and liver damage when combined with NSAIDs like Lornoxicam.

Interaction with Lab Tests:

• Liver Function Test:
  • Lornoxicam can elevate certain liver enzymes, which may lead to false-positive results in liver function tests. It's important to inform the healthcare provider about the use of this medication at least a week before undergoing any liver function tests.

Interaction with Other Medications:

Methotrexate:

• Co-administration increases the risk of adverse effects on the heart and blood vessels. Careful monitoring and dose adjustment may be required.

Tacrolimus:

• Combining Lornoxicam with Tacrolimus may require dose adjustments and frequent monitoring due to the potential for enhanced toxicity.

Warfarin:

• Lornoxicam can interact with Warfarin, increasing the risk of bleeding. Dose adjustments and regular monitoring of blood clotting parameters (INR) are essential.

Digoxin:

• When taken together with Digoxin, the risk of adverse cardiovascular effects is heightened. Close monitoring is necessary.

Theophylline:

• If you're taking Theophylline (for asthma or COPD), combining it with Lornoxicam may require dose adjustments and frequent monitoring.

Cimetidine:

• Combining with Cimetidine (a medication used for reducing stomach acid) may increase the blood levels of Lornoxicam, leading to potential side effects. Monitoring and dose adjustments may be required.

Interaction with Diseases:

Asthma:

• Lornoxicam should be used with extreme caution in individuals with asthma or COPD, as NSAIDs can worsen symptoms of respiratory diseases and increase the risk of bronchospasm.

Cerebrovascular Oedema:

• This drug should be used with caution in patients with fluid retention conditions, especially related to heart disease. Close monitoring is required to avoid complications related to fluid buildup.

Hemorrhagic Disorders:

• Lornoxicam is contraindicated in patients with internal bleeding or hemorrhagic disorders (e.g., gastrointestinal bleeding). The risk of fatal side effects is high in such cases, and an alternative medication should be prescribed.

✔️ Do Not Take Ornopain 4 Tablet If You Have:

• Allergic reactions to any of its components.
• Thrombocytopenia (low platelet count).
• Gastrointestinal bleeding or other bleeding disorders.
• Peptic ulcers (open sores in the stomach or intestines).
• Severe heart, liver, or kidney problems.
• History of gastrointestinal bleeding or perforation linked to NSAID use.

✔️ Pregnancy & Lactation

• Pregnancy: Ornopain 4 should not be taken during the last three months of pregnancy.
• Breastfeeding: Consult your doctor before using Ornopain 4 if you are breastfeeding.

✔️ Inform Your Doctor If You Have:

• Impaired kidney or liver function.
• High blood pressure.
• Heart failure.
• Ulcerative colitis or Crohn’s disease (inflammatory bowel disease).
• Asthma.
• Lupus erythematosus (auto-immune condition).
• Diabetes.
• Blood coagulation disorders (bleeding or clotting issues).

✔️ Storage:

This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.